| Item Type | Name |
|
Concept
|
Acute Disease
|
|
Concept
|
Actins
|
|
Concept
|
Adaptation, Biological
|
|
Concept
|
Anemia, Aplastic
|
|
Concept
|
Aged, 80 and over
|
|
Concept
|
Autophagy
|
|
Concept
|
Adaptation, Physiological
|
|
Concept
|
Acyl Coenzyme A
|
|
Concept
|
Aged
|
|
Concept
|
Amino Acids
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
|
Concept
|
Arginine
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Movement
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Binding Sites
|
|
Concept
|
beta-Galactosidase
|
|
Concept
|
Brain
|
|
Concept
|
Capillary Permeability
|
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
|
Concept
|
Cell Division
|
|
Concept
|
Central Nervous System
|
|
Concept
|
Cell Cycle
|
|
Concept
|
Hematopoiesis
|
|
Concept
|
Leukemia, Erythroblastic, Acute
|
|
Concept
|
Cytoskeleton
|
|
Concept
|
Dogs
|
|
Concept
|
Gluconeogenesis
|
|
Concept
|
Endoplasmic Reticulum
|
|
Concept
|
Erythroblasts
|
|
Concept
|
Erythropoietin
|
|
Concept
|
Disease Susceptibility
|
|
Concept
|
Fasting
|
|
Concept
|
Nucleic Acid Hybridization
|
|
Concept
|
Histocytochemistry
|
|
Concept
|
Erythrocytes, Abnormal
|
|
Concept
|
Erythropoiesis
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Longevity
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Mitosis
|
|
Concept
|
Poly(ADP-ribose) Polymerases
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Orchiectomy
|
|
Concept
|
NADP
|
|
Concept
|
Necrosis
|
|
Concept
|
Glycolysis
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Nude
|
|
Concept
|
Middle Aged
|
|
Concept
|
HeLa Cells
|
|
Concept
|
Phosphorylation
|
|
Concept
|
NAD
|
|
Concept
|
Embryonic and Fetal Development
|
|
Concept
|
Protein Binding
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Receptors, Androgen
|
|
Concept
|
Rabbits
|
|
Concept
|
Quail
|
|
Concept
|
Sequence Homology, Nucleic Acid
|
|
Concept
|
Quinoxalines
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Humans
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Protein Biosynthesis
|
|
Concept
|
Intracellular Membranes
|
|
Concept
|
Biomarkers, Tumor
|
|
Concept
|
Dinoprostone
|
|
Concept
|
Ultraviolet Rays
|
|
Concept
|
Biomarkers
|
|
Concept
|
Lysosomes
|
|
Concept
|
Focal Adhesions
|
|
Concept
|
S Phase
|
|
Concept
|
Up-Regulation
|
|
Concept
|
G1 Phase
|
|
Concept
|
Mitochondria
|
|
Concept
|
Cyclic AMP Response Element-Binding Protein
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Mitochondria, Liver
|
|
Concept
|
Myosins
|
|
Concept
|
Apoptosis
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
ras Proteins
|
|
Concept
|
Carcinoma, Ductal, Breast
|
|
Concept
|
Protein Transport
|
|
Concept
|
Myelopoiesis
|
|
Concept
|
Proto-Oncogene Proteins c-ets
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Tumor Burden
|
|
Concept
|
Cell Growth Processes
|
|
Concept
|
Interleukin-1beta
|
|
Concept
|
Amino Acid Motifs
|
|
Concept
|
Databases, Genetic
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p21
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Phagosomes
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Microphthalmia-Associated Transcription Factor
|
|
Concept
|
Lipoylation
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
Rats
|
|
Concept
|
Paxillin
|
|
Concept
|
Retinoblastoma-Binding Protein 1
|
|
Concept
|
Class I Phosphatidylinositol 3-Kinases
|
|
Concept
|
Immunoprecipitation
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Cyclins
|
|
Concept
|
Cell Death
|
|
Concept
|
Proto-Oncogene Proteins p21(ras)
|
|
Concept
|
Cyclin-Dependent Kinases
|
|
Concept
|
Carcinoma, Pancreatic Ductal
|
|
Concept
|
Anoikis
|
|
Concept
|
Gadolinium DTPA
|
|
Concept
|
E2F1 Transcription Factor
|
|
Concept
|
Cell Cycle Checkpoints
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Protein Stability
|
|
Concept
|
Carcinoma, Intraductal, Noninfiltrating
|
|
Concept
|
Chickens
|
|
Concept
|
Data Interpretation, Statistical
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Erythrocytes
|
|
Concept
|
Hemagglutinins
|
|
Concept
|
Kinetics
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
U937 Cells
|
|
Concept
|
Lipogenesis
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Academic Article
|
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system.
|
|
Academic Article
|
Insights into cancer from transgenic mouse models.
|
|
Academic Article
|
Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.
|
|
Academic Article
|
A novel form of pRb expressed during normal myelopoiesis and in tumour-associated macrophages.
|
|
Academic Article
|
Hypoxic stress underlies defects in erythroblast islands in the Rb-null mouse.
|
|
Academic Article
|
Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3.
|
|
Academic Article
|
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
|
|
Academic Article
|
Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis.
|
|
Academic Article
|
c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.
|
|
Academic Article
|
New paradigms for the function of JNKK1/MKK4 in controlling growth of disseminated cancer cells.
|
|
Academic Article
|
The Rb tumor suppressor in stress responses and hematopoietic homeostasis.
|
|
Academic Article
|
New roles for the RB tumor suppressor protein.
|
|
Academic Article
|
The Rb tumor suppressor is required for stress erythropoiesis.
|
|
Academic Article
|
Elevated poly-(ADP-ribose)-polymerase activity sensitizes retinoblastoma-deficient cells to DNA damage-induced necrosis.
|
|
Academic Article
|
The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system.
|
|
Academic Article
|
Autophagy: assays and artifacts.
|
|
Academic Article
|
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.
|
|
Academic Article
|
BNip3 regulates mitochondrial function and lipid metabolism in the liver.
|
|
Academic Article
|
Autophagy: cellular and molecular mechanisms.
|
|
Academic Article
|
Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.
|
|
Academic Article
|
The RB tumor suppressor: a gatekeeper to hormone independence in prostate cancer?
|
|
Academic Article
|
Effects of hypoxia on heterotypic macrophage interactions.
|
|
Academic Article
|
Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts.
|
|
Academic Article
|
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.
|
|
Academic Article
|
MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression.
|
|
Academic Article
|
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos.
|
|
Academic Article
|
High resolution 3D MRI of mouse mammary glands with intra-ductal injection of contrast media.
|
|
Academic Article
|
Mammary cancer initiation and progression studied with magnetic resonance imaging.
|
|
Academic Article
|
Measuring autophagy in stressed cells.
|
|
Academic Article
|
Correlation of In Vivo and Ex Vivo ADC and T2 of In Situ and Invasive Murine Mammary Cancers.
|
|
Academic Article
|
Tumor suppressor functions of BNIP3 and mitophagy.
|
|
Academic Article
|
Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis.
|
|
Academic Article
|
GATAAG; a cis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression.
|
|
Academic Article
|
Derepression of mouse beta-major-globin gene transcription during erythroid differentiation.
|
|
Academic Article
|
cis and trans control of erythroid cell-specific gene expression during erythropoiesis.
|
|
Academic Article
|
Characterization, evolutionary relationships, and chromosome location of processed mouse HPRT pseudogene.
|
|
Academic Article
|
Regulation of erythroid cell-specific gene expression during erythropoiesis.
|
|
Academic Article
|
Pax-QNR/Pax-6, a paired- and homeobox-containing protein, recognizes Ets binding sites and can alter the transactivating properties of Ets transcription factors.
|
|
Academic Article
|
The ets gene family.
|
|
Academic Article
|
Regulation of erythroid-specific gene expression.
|
|
Academic Article
|
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
|
|
Academic Article
|
Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3.
|
|
Academic Article
|
Novel insights into how autophagy regulates tumor cell motility.
|
|
Academic Article
|
In Brief: Mitophagy: mechanisms and role in human disease.
|
|
Academic Article
|
Autophagy in cancer metastasis.
|
|
Academic Article
|
Small molecules inhibit STAT3 activation, autophagy, and cancer cell anchorage-independent growth.
|
|
Academic Article
|
Expanding perspectives on the significance of mitophagy in cancer.
|
|
Academic Article
|
Dia1-dependent adhesions are required by epithelial tissues to initiate invasion.
|
|
Academic Article
|
Functions of autophagy in the tumor microenvironment and cancer metastasis.
|
|
Academic Article
|
mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors.
|
|
Academic Article
|
Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.
|
|
Academic Article
|
Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer.
|
|
Academic Article
|
Autophagy and cancer cell metabolism.
|
|
Academic Article
|
BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.
|
|
Academic Article
|
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
|
|
Academic Article
|
Autophagy in major human diseases.
|
|
Academic Article
|
ULK1 promotes mitophagy via phosphorylation and stabilization of BNIP3.
|
|
Academic Article
|
Lipid droplet turnover at the lysosome inhibits growth of hepatocellular carcinoma in a BNIP3-dependent manner.
|
|
Concept
|
Poly(ADP-ribose) Polymerase Inhibitors
|
|
Concept
|
Autophagy-Related Protein-1 Homolog
|
|
Concept
|
Sequestosome-1 Protein
|
|
Concept
|
Autophagosomes
|
|
Concept
|
Autophagy-Related Protein 8 Family
|
|
Concept
|
A549 Cells
|
|
Concept
|
Cancer-Associated Fibroblasts
|
|
Concept
|
MCF-7 Cells
|
|
Concept
|
Molecular Docking Simulation
|
|
Concept
|
Triple Negative Breast Neoplasms
|
|
Academic Article
|
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
|
|
Academic Article
|
DISSECTING TUMOR TRANSCRIPTIONAL HETEROGENEITY FROM SINGLE-CELL RNA-SEQ DATA BY GENERALIZED BINARY COVARIANCE DECOMPOSITION.
|